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A pszilocibin gomba serkenti az agysejtek regenerálódását és kialakulását

2015.10.11

A cikket forditottaVaultKnowledge | orichalcum workshop
Az eredeti cikk: 
http://timewheel.net/filter/blog/Tome-Psilocyb..

 

psilo.jpgPszilocibin - a pszichoaktív gombafajták nootropikus vegyülete - úgy tűnik kulcsfontosságú szerepet tölt be a mentális betegségek gyógyításában, illetve az elvesztett kognitív képességek helyreállításában. Egy, az 'Experimental Brain Research' tudományos folyóiratban megjelent tanulmány szerint, Dr. Juan R. Sanchez a pszilocibin azon képességét vizsgálta, mely bizonyos receptorok összekapcsolásával a gyógyulást és a gyarapodást stimulálja. Az eredmények kimutatták, hogy a pszilocibin elmére gyakorolt hatása élénkíti a sérült agysejtek helyreállítását, és ugyancsak rendkívül hatékony a depresszió és a poszttraumatikus stressz szindróma (PTSD) kezelésében.

 

A kísérletben az egereket arra kondicionálták, hogy egy bizonyos hang lejátszását követően áramütést kapnak, majd ezeket aztán pszilocibinnel kezelték és összehasonlították azokkal a kísérleti egerekkel, amelyek csupán sóoldatos kezelést kaptak. A kutatás kimutatta, hogy azok az egerek, melyek egy pontosan kiszámolt pszilocibin dózist kaptak, a hang lejátszását követően alig, vagy egyáltalán nem mutattak félelmet. Ezzel szemben a sóoldattal kezelt egerek viselkedését továbbra is a páni félelem jellemezte minden alkalommal. Egyes egerek sokkal nagyobb dózisban kaptak pszilocibint, ami viszont nagyobb, még intenzívebb félelem reakciót váltott ki bennük, mint korábban. Ez jól mutatja, hogy ha a cél az, hogy a pszilocibint elismerjék gyógyszerként, akkor meg kell adni a neki járó tiszteletet.

 

tw_brain-reparation_780.png

 

„Az, hogy a pszilocibin hatással van a kognícióra és stimulálja a hippokampuszban bekövetkező neurogenézist, alapos bizonyíték támasztja alá. A szerotonin (5-hidroxitriptamin vagy 5-HT) bizonyos 5-HT receptorok altípusaira (feltehetően az 5-HT2A receptorokra) való hatása összefüggésben van a hippokampuszban történő sejtfejlődés szabályozásával. Az állatokon folytatott kísérletek eredményei eléggé meggyőzőek ahhoz, hogy további kutatásokat végezzünk azzal kapcsolatban, hogy vajon a pszilocibin valóban serkenti-e a neurogenézist és mérhető javulást eredményez a tanulásban.” - Mondja Dr. Sanchez-Ramos

 

A pszilocibint nootropikus szerként tartják számon, mivel közvetlen hatással van a hippokampusz – a memória és érzelmi központ, és az autonóm idegrendszer egészségére. Az egészséges hippokampusz jellemzője a fokozott tanulási képesség és a rövid távú emlékek hatékony feldolgozása a hosszú távú memóriába. A pszilocibin által előidézett agysejt-fejlődés tehát egyet jelent a még egészségesebb és élesebben működő aggyal.

 

A kutatás nagy része még mindig folyamatban van, de most már magabiztossággal kijelenthetjük, hogy közeleg az idő, mikor a pszilocibin végre a pszichiátriai kezelés egy legális formája lesz. Azok számára, akik életét folytonos pszichiátriai problémák kísértik, egy professzionális környezetben történő pszilocibin terápia szó szerint a boldogságot jelentő kulcs lehet. Kissé ironikus, hogy egy ilyen gyógyászati potenciállal rendelkező, természetben előforduló szer évtizedek óta be van tiltva, mert „nincs gyógyászati haszna és túl nagy a kockázata annak, hogy visszaélnek vele.”

 

Catlow, Briony J., Shijie Song, Daniel A. Paredes, Cheryl L. Kirstein, and Juan Sanchez-Ramos. "Effects of Psilocybin on Hippocampal Neurogenesis and Extinction of Trace Fear Conditioning." Experimental Brain Research(n.d.): n. pag. ISSN 0014-4819. Web.

 

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